• 产品编号:Asc-289
    • 产品名称:TMCB
    • 产品规格:10mg/50mg
    • 价  格:840.00/3540.00
    • 供 应 商:Ascent
    • 库  存:
  • TMCB

    selective CK2 inhibitor(选择性CK2抑制剂)
    Purity: >98%

    Biological Description
    CK2 inhibitor (Ki = 0.25 μM), more selective than DMAT. Unlike DMAT, TMCB displays selectivity over PIM1, HIPK2 and DYRK1a (Ki values are 8.65, 15.25 and 11.90 μM respectively) and a more favourable selectivity profile over a range of other kinases.

    Useful References
    Pagona et al (2008) The selectivity of inhibitors of protein kinase CK2: an update. Biochem J. 415:353-65 abstract

    Chemical Information
    2-(4,5,6,7-Tetrabromo-2-(dimethylamino)-1H-benzo[d]imidazol-1-yl)acetic acid
     

    • Store at RT
    • MW 534.82
    • Soluble in DMSO
    • C11H9Br4N3O2
    • 905105-89-7


     

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